Primary-Residence-Only Rule
Unincorporated Lee County's code does not require a short-term rental to be your primary residence. The one owner-occupancy rule in the Land Development Code applies to bed and breakfast establishments, which must be owner-occupied unless approved inside a PRFPD.
Owner-Occupancy Rules for Lee County Rentals
Some RestrictionsLee County Land Development Code § 34-2 (bed and breakfast establishment); § 34-1493(b)(1)
A local law, ordinance, or regulation may not prohibit vacation rentals or regulate the duration or frequency of rental of vacation rentals. This paragraph does not apply to any local law, ordinance, or regulation adopted on or before June 1, 2011.