St. Louis, MO Cannabis Regulations: Dispensary Zoning (2026)
Key Facts
- Dispensaries
- conditional in F, by-right G through L
- Cultivation/manufacturing
- conditional in H, by-right I through L
- Testing facilities
- by-right only in I through L
- Residential districts A-E
- all marijuana uses prohibited
- Curbside/extended-hours dispensaries
- always need conditional use permit
Summary
St. Louis confines marijuana dispensaries, cultivation, manufacturing, and testing facilities to its commercial and industrial zoning districts, requiring a conditional use permit in some and prohibiting them outright in every residential district from 'A' through 'E'.
The following Use Table lists how Marijuana Facilities are regulated in the various zoning districts... whether the use is Permitted (P), whether it requires a Conditional Use Permit (C), or whether it is prohibited (NA). Comprehensive Marijuana Dispensary Facility, Medical Marijuana Dispensary Facility, and Microbusiness Dispensary Facility NA NA NA NA NA C P P P P P P
Official source re-checked September 7, 2026: no newer edition of the code had been published (publisher’s edition: Code of Ordinances: Supplement 11).
Full Breakdown
St. Louis Zoning Code § 26.70.030 sets a use table for marijuana facilities across its lettered zoning districts. Cultivation and marijuana-infused product manufacturing facilities are barred in the 'A' through 'G' districts, allowed only with a conditional use permit in the 'H' Area Commercial District, and permitted by right from 'I' Central Business through 'L' Jefferson Memorial. Testing facilities are allowed only in 'I' through 'L', with no conditional-use option elsewhere. Dispensaries need a conditional use permit in 'F' Neighborhood Commercial and are permitted by right from 'G' Local Commercial and Office through 'L'; adding curbside pickup, a sales window, or extended hours turns even a 'G' through 'L' dispensary into a conditional use.
Violations & Fines
Operating in a prohibited zone or violating conditional-use terms is a Chapter 1.12 infraction; the City Counselor can also sue to enjoin the use, and a violated conditional use permit gets revoked, barring reapplication for one year.
Frequently Asked Questions
Can a marijuana dispensary open in a St. Louis strip mall?
Where can a marijuana cultivation facility locate in St. Louis?
Sources & Official References
Other rules in St. Louis
Compare St. Louis to another location·View the Missouri cannabis regulations overview
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