Skip to main content
CityRuleLookup

Cannabis Regulations in Missouri (2026)

34 rules on the books across Missouri, 15 cities and counties. Select a rule to read the full details.

Severity: Few Restrictions · Light Restrictions · Some Restrictions · Significant Restrictions · Heavy Restrictions

Dispensary Zoning

Where cannabis businesses may locate, the zones that allow retail, the buffer distances from schools and parks, and the cities that ban commercial cannabis activity entirely.

Missouri: statewide

StatewideSome Restrictions

Missouri Article XIV authorizes state-licensed marijuana dispensaries and limits local control to non-prohibitive…

Read full rule →

Lees Summit

Heavy Restrictions

A Lee's Summit dispensary needs a state DHSS license and a city marijuana dispensary business license, must sit in an…

Read full rule →

Columbia

Significant Restrictions

Columbia, Missouri has not opted out of marijuana licensing: dispensaries are permitted in the M-C, M-DT, and IG zoning…

Read full rule →

Independence

Significant Restrictions

Independence allows marijuana dispensaries and cultivation facilities only as conditional uses in C-2, C-3 and I-1…

Read full rule →

Kirkwood

Significant Restrictions

Kirkwood confines marijuana dispensaries to a special use permit in the B-3 District, with cultivation, infused-product…

Read full rule →

O Fallon

Significant Restrictions

O'Fallon's Zoning Code limits the entire city to ten marijuana dispensary facilities and shuts the Downtown Overlay…

Read full rule →

St Charles County

Significant Restrictions

St. Charles County has not opted out of hosting marijuana facilities: it taxes adult-use sales at 3% under § 140.100…

Read full rule →

Cass County

Some Restrictions

Cass County Code § 400.261 controls where marijuana businesses, including dispensaries, cultivation and processing…

Read full rule →

Clay County

Some Restrictions

Cannabis dispensaries are legal and operating in Clay County, licensed by the state. Local governments can regulate…

Read full rule →

Florissant

Some Restrictions

Florissant's zoning code confines licensed marijuana businesses to specific commercial and industrial districts rather…

Read full rule →

Greene County

Some Restrictions

Unincorporated Greene County allows medical marijuana dispensaries only in C-1, C-2, C-3, M-1 and M-2 zones, with…

Read full rule →

Jackson County

Some Restrictions

Marijuana cultivation, dispensary, manufacturing and testing facilities are allowed in specific unincorporated Jackson…

Read full rule →

Kansas City

Some Restrictions

Kansas City confines licensed marijuana dispensaries, cultivation, manufacturing and testing facilities to zoning…

Read full rule →

Springfield

Some Restrictions

Springfield permits marijuana cultivation, wholesale, testing, and manufacturing facilities as of-right uses in its…

Read full rule →

St. Louis

Some Restrictions

St. Louis confines marijuana dispensaries, cultivation, manufacturing, and testing facilities to its commercial and…

Read full rule →

St. Louis County

Some Restrictions

St. Louis County has not opted out of marijuana dispensaries: its zoning code lists them as a by-right permitted use in…

Read full rule →

Buffer Zones

Required minimum distances between cannabis retailers and sensitive uses (schools, parks, day-cares), and between cannabis retailers themselves.

Florissant

Significant Restrictions

Florissant's zoning code keeps licensed marijuana facilities away from sensitive uses with two different buffers: a…

Read full rule →

Independence

Significant Restrictions

Marijuana facilities in Independence can't locate within 1,000 feet of an existing school, day care, or church…

Read full rule →

Kansas City

Significant Restrictions

Kansas City requires marijuana facilities to sit 1,000 feet from schools, 300 feet from churches and daycares, and…

Read full rule →

Kirkwood

Significant Restrictions

Kirkwood requires marijuana facilities to sit at least 1,000 feet from a church, school or child day-care center, and…

Read full rule →

O Fallon

Significant Restrictions

O'Fallon keeps marijuana cultivation, manufacturing and dispensary facilities at least 750 feet from any existing…

Read full rule →

St Charles County

Significant Restrictions

St. Charles County keeps medical marijuana facilities a minimum of 1,000 feet from churches, schools, residential…

Read full rule →

Cass County

Some Restrictions

Cass County Code § 400.261(B)(1) keeps new medical and marijuana facilities at least 1,000 feet from any then-existing…

Read full rule →

Columbia

Some Restrictions

Columbia, Missouri bars marijuana facilities within 500 feet of a school, day care center, or church.

Read full rule →

Greene County

Some Restrictions

Greene County requires medical marijuana facilities to sit at least 1,000 feet from schools, daycares, and churches…

Read full rule →

Jackson County

Some Restrictions

Unincorporated Jackson County limits medical marijuana cultivation, dispensary, manufacturing and testing facilities to…

Read full rule →

Springfield

Some Restrictions

Springfield bars new marijuana and medical marijuana facilities from siting within 1,000 feet of an existing elementary…

Read full rule →

St. Louis

Some Restrictions

Missouri requires comprehensive cannabis facilities to be at least 1,000 feet from schools, daycares, and churches…

Read full rule →

St. Louis County

Some Restrictions

A marijuana dispensary in unincorporated St. Louis County must clear two hard buffers to open as a permitted use: 1,000…

Read full rule →

Personal Cultivation Limits

Maximum number of plants residents may grow at home for personal use, indoor-vs-outdoor rules, and visibility/odor mitigation requirements.