Cannabis Regulations in Missouri (2026)
34 rules on the books across Missouri, 15 cities and counties. Select a rule to read the full details.
Severity: Few Restrictions · Light Restrictions · Some Restrictions · Significant Restrictions · Heavy Restrictions
Home Cultivation
Rules for growing cannabis plants at home, including plant count limits, indoor vs. outdoor growing, and visibility and odor requirements.
Missouri: statewide
StatewideFew RestrictionsMissouri Constitution Article XIV grants registered adults age 21 and over the right to cultivate up to six flowering…
Read full rule →Clay County
Some RestrictionsGrowing cannabis at home is legal in Clay County for adults 21 and over who hold a $100 state registration card. The…
Read full rule →Kansas City
Some RestrictionsMissouri legalized recreational marijuana through Amendment 3 in November 2022, which permits adults 21 and older to…
Read full rule →Lees Summit
Some RestrictionsAdults 21 and older in Lee's Summit may grow up to six flowering, six nonflowering, and six clone marijuana plants with…
Read full rule →Dispensary Zoning
Where cannabis businesses may locate, the zones that allow retail, the buffer distances from schools and parks, and the cities that ban commercial cannabis activity entirely.
Missouri: statewide
StatewideSome RestrictionsMissouri Article XIV authorizes state-licensed marijuana dispensaries and limits local control to non-prohibitive…
Read full rule →Lees Summit
Heavy RestrictionsA Lee's Summit dispensary needs a state DHSS license and a city marijuana dispensary business license, must sit in an…
Read full rule →Columbia
Significant RestrictionsColumbia, Missouri has not opted out of marijuana licensing: dispensaries are permitted in the M-C, M-DT, and IG zoning…
Read full rule →Independence
Significant RestrictionsIndependence allows marijuana dispensaries and cultivation facilities only as conditional uses in C-2, C-3 and I-1…
Read full rule →Kirkwood
Significant RestrictionsKirkwood confines marijuana dispensaries to a special use permit in the B-3 District, with cultivation, infused-product…
Read full rule →O Fallon
Significant RestrictionsO'Fallon's Zoning Code limits the entire city to ten marijuana dispensary facilities and shuts the Downtown Overlay…
Read full rule →St Charles County
Significant RestrictionsSt. Charles County has not opted out of hosting marijuana facilities: it taxes adult-use sales at 3% under § 140.100…
Read full rule →Cass County
Some RestrictionsCass County Code § 400.261 controls where marijuana businesses, including dispensaries, cultivation and processing…
Read full rule →Clay County
Some RestrictionsCannabis dispensaries are legal and operating in Clay County, licensed by the state. Local governments can regulate…
Read full rule →Florissant
Some RestrictionsFlorissant's zoning code confines licensed marijuana businesses to specific commercial and industrial districts rather…
Read full rule →Greene County
Some RestrictionsUnincorporated Greene County allows medical marijuana dispensaries only in C-1, C-2, C-3, M-1 and M-2 zones, with…
Read full rule →Jackson County
Some RestrictionsMarijuana cultivation, dispensary, manufacturing and testing facilities are allowed in specific unincorporated Jackson…
Read full rule →Kansas City
Some RestrictionsKansas City confines licensed marijuana dispensaries, cultivation, manufacturing and testing facilities to zoning…
Read full rule →Springfield
Some RestrictionsSpringfield permits marijuana cultivation, wholesale, testing, and manufacturing facilities as of-right uses in its…
Read full rule →St. Louis
Some RestrictionsSt. Louis confines marijuana dispensaries, cultivation, manufacturing, and testing facilities to its commercial and…
Read full rule →St. Louis County
Some RestrictionsSt. Louis County has not opted out of marijuana dispensaries: its zoning code lists them as a by-right permitted use in…
Read full rule →Buffer Zones
Required minimum distances between cannabis retailers and sensitive uses (schools, parks, day-cares), and between cannabis retailers themselves.
Florissant
Significant RestrictionsFlorissant's zoning code keeps licensed marijuana facilities away from sensitive uses with two different buffers: a…
Read full rule →Independence
Significant RestrictionsMarijuana facilities in Independence can't locate within 1,000 feet of an existing school, day care, or church…
Read full rule →Kansas City
Significant RestrictionsKansas City requires marijuana facilities to sit 1,000 feet from schools, 300 feet from churches and daycares, and…
Read full rule →Kirkwood
Significant RestrictionsKirkwood requires marijuana facilities to sit at least 1,000 feet from a church, school or child day-care center, and…
Read full rule →O Fallon
Significant RestrictionsO'Fallon keeps marijuana cultivation, manufacturing and dispensary facilities at least 750 feet from any existing…
Read full rule →St Charles County
Significant RestrictionsSt. Charles County keeps medical marijuana facilities a minimum of 1,000 feet from churches, schools, residential…
Read full rule →Cass County
Some RestrictionsCass County Code § 400.261(B)(1) keeps new medical and marijuana facilities at least 1,000 feet from any then-existing…
Read full rule →Columbia
Some RestrictionsColumbia, Missouri bars marijuana facilities within 500 feet of a school, day care center, or church.
Read full rule →Greene County
Some RestrictionsGreene County requires medical marijuana facilities to sit at least 1,000 feet from schools, daycares, and churches…
Read full rule →Jackson County
Some RestrictionsUnincorporated Jackson County limits medical marijuana cultivation, dispensary, manufacturing and testing facilities to…
Read full rule →Springfield
Some RestrictionsSpringfield bars new marijuana and medical marijuana facilities from siting within 1,000 feet of an existing elementary…
Read full rule →St. Louis
Some RestrictionsMissouri requires comprehensive cannabis facilities to be at least 1,000 feet from schools, daycares, and churches…
Read full rule →St. Louis County
Some RestrictionsA marijuana dispensary in unincorporated St. Louis County must clear two hard buffers to open as a permitted use: 1,000…
Read full rule →Personal Cultivation Limits
Maximum number of plants residents may grow at home for personal use, indoor-vs-outdoor rules, and visibility/odor mitigation requirements.