Cannabis Regulations in O'Fallon, MO (2026)
2 verified cannabis regulations for O'Fallon, Missouri, sourced directly from the municipal code and official government pages.
Verified from official government sources
Dispensary Zoning
O'Fallon's Zoning Code limits the entire city to ten marijuana dispensary facilities and shuts the Downtown Overlay District out of that count entirely. Section 400.245 also runs dispensaries through a two-step approval: a Site Review Permit that checks zoning compliance before State licensing, then a City business license the operator must keep current or face closure.
O'Fallon Caps Marijuana Dispensaries At Ten
Significant RestrictionsO'Fallon Code § 400.245(C), (P)
C. No more than a total of ten (10) marijuana dispensary facilities will be allowed within the City limits. Marijuana dispensaries are not permitted within the Downtown Overlay District. ... P. Each facility shall at all times possess a current City business license. By obtaining a City business license, the facility licensee irrevocably consents to the immediate closure and cessation of operat...
Buffer Zones
O'Fallon keeps marijuana cultivation, manufacturing and dispensary facilities at least 750 feet from any existing school, licensed daycare or church, and 1,500 feet from another marijuana facility of the same type, under Zoning Code Section 400.245(D). A narrow pharmacy exception and an industrial-district carve-out for manufacturing facilities soften the second buffer.
O'Fallon Marijuana Buffer From Schools, Churches
Significant RestrictionsO'Fallon Code § 400.245(D)(1)-(2)
1. No marijuana-related uses shall be operated or maintained within seven hundred fifty (750) feet of any then-existing elementary or secondary school, child daycare center or church. 2. No marijuana-related uses shall be operated or maintained within one thousand five hundred (1,500) feet of another marijuana facility of identical use except when marijuana sales represent less than five percen...
Looking for St. Charles County county-wide rules?
County ordinances apply to unincorporated areas and may supplement O'Fallon city rules.
Cannabis Regulations in St. Charles County →