Cannabis Regulations in St. Louis, MO (2026)
6 verified cannabis regulations for St. Louis, Missouri, sourced directly from the municipal code and official government pages.
Verified from official government sources
Home Cultivation
Missouri Amendment 3 (2022) allows adults 21+ with a cultivation identification card to grow up to 6 flowering plants, 6 nonflowering plants, and 6 clones at home. Plants must be in a locked, enclosed, non-public space. St. Louis cannot ban home cultivation by registered users.
Cannabis: Home Cultivation
Some RestrictionsDispensary Zoning
St. Louis allows state-licensed medical and adult-use (comprehensive) dispensaries in designated zoning districts subject to a 1,000-foot buffer from schools, daycares, and churches. Local operators must hold DHSS licenses and obtain City of St. Louis business licenses and occupancy permits.
Cannabis: Dispensary Zoning
Some RestrictionsBuffer Zones
Missouri requires comprehensive cannabis facilities to be at least 1,000 feet from schools, daycares, and churches under Article XIV. St. Louis enforces buffers via zoning review by the Cannabis Regulation Division.
Cannabis facility buffer distances
Some RestrictionsRSMo § 195.005
195.005. Comprehensive drug control act. — This chapter and chapter 579 shall be known as the "Comprehensive Drug Control Act".
Cannabis Delivery Rules
Missouri Division of Cannabis Regulation authorizes licensed dispensaries to offer delivery and curbside pickup statewide. St. Louis dispensaries follow state delivery rules with no additional city ordinance restriction.
Cannabis delivery and curbside
Some RestrictionsPersonal Cultivation Limits
Missouri Article XIV allows registered adults 21 and over to home-cultivate up to six flowering plants, six immature plants, and six clones in a secure, locked indoor space invisible from public view.
Social Equity Licensing
Missouri Article XIV created a microbusiness program issuing licenses by lottery to applicants meeting social-equity criteria, including residents of high-incarceration ZIP codes that include parts of St. Louis.
Microbusiness social equity licenses
Few Restrictions