O'Fallon, MO Home Business: Zoning & Home Occupation Permits (2026)

280(D)(1) requires the structure where it operates to already carry a valid occupancy permit. 280(C), disclosing the business name and nature, the responsible resident, the number of residents plus employees or customers who may be on site at once (capped at the structure's maximum occupancy), the on-site parking available, a description of goods or services, any special equipment, and, for rental property, the landlord's written consent. 280(D)(3) then sets the physical size limit: the business must be conducted entirely within an enclosed structure and cannot occupy more than twenty-five percent of the main residential building's floor area, and in no case more than five hundred square feet, so that the home's use for the business stays 'clearly incidental and subordinate' to its use as a residence.

280(D)(4) bars any exterior alteration that changes the building's character as a residence and forbids visible evidence of the business from outside, and (D)(5) prohibits any outdoor storage of business materials or equipment. 280(D)(14) makes any registration non-transferable, so it terminates when the property is sold.