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Cannabis Regulations in Port St. Lucie, FL (2026)

2 verified cannabis regulations for Port St. Lucie, Florida, sourced directly from the municipal code and official government pages.

Verified from official government sources

Dispensary Zoning

Port St. Lucie allows Medical Marijuana Dispensing Facilities as a permitted use in the General Commercial (CG) and Industrial (IN) zoning districts, and as a special exception in Service Commercial (CS), under the city's zoning code. Chapter 120 then layers on its own permitting, security, and hours-of-operation requirements before a dispensary can open.

Cannabis Dispensary Zoning in Port St. Lucie

Some Restrictions

Port St. Lucie Code of Ordinances § 158.124(B)(14); § 158.126(D)(17); § 158.136(B)(1)(o)

(B)Permitted Principal Uses and Structures. The following principal uses and structures are permitted... (14)Medical Marijuana Dispensing Facilities as set forth in Chapter 120. ... (D)Special Exception Uses. The following uses may be permitted only following the review and specific approval thereof by the City Council:... (17)Medical Marijuana Dispensing Facilities. ... o.Medical Marijuana Dis...

Buffer Zones

Medical Marijuana Dispensing Facilities in Port St. Lucie must sit at least 500 feet from any existing public or private preschool, elementary, middle, or high school, measured under Code of Ordinances § 120.03(A). The buffer is calculated property line to property line in a straight line, without regard to any building standing in between.

Cannabis Dispensary Buffer Zones in Port St. Lucie

Some Restrictions

Port St. Lucie Code of Ordinances § 120.03(A)(1)-(3)

(A)No Dispensing Facility shall be located within:(1)A five hundred (500) foot radius of an existing public or private preschool, elementary school, middle school, high school.(2)The distances specified in this section shall be determined by the horizontal distance measured in a straight line from the closest property line to the closest property line of the lot on which the Dispensing Facility...

Looking for St. Lucie County county-wide rules?

County ordinances apply to unincorporated areas and may supplement Port St. Lucie city rules.

Cannabis Regulations in St. Lucie County